T . L . Dutka and G . D . Lamb glycolysis skeletal muscle fibers preferentially use ATP from Na + - K + pumps in the transverse tubular system of

نویسندگان

  • T. L. Dutka
  • G. D. Lamb
چکیده

[PDF] [Full Text] [Abstract] , January 1, 2008; 88 (1): 287-332. Physiol Rev D. G. Allen, G. D. Lamb and H. Westerblad Skeletal Muscle Fatigue: Cellular Mechanisms [PDF] [Full Text] [Abstract] , February 1, 2008; 586 (3): 875-887. J. Physiol. T. L. Dutka, R. M. Murphy, D. G. Stephenson and G. D. Lamb importance in excitation-contraction coupling and fatigue Chloride conductance in the transverse tubular system of rat skeletal muscle fibres: [PDF] [Full Text] [Abstract] , March 1, 2008; 586 (5): 1447-1459. J. Physiol. Bangsbo N. Nordsborg, J. Ovesen, M. Thomassen, M. Zangenberg, C. Jons, F. M. Iaia, J. J. Nielsen and J. K+ homeostasis during exercise in humans Effect of dexamethasone on skeletal muscle Na+,K+ pump subunit specific expression and [PDF] [Full Text] [Abstract] , September 1, 2008; 586 (17): 4039-4054. J. Physiol. S. P. Cairns and M. I. Lindinger Do multiple ionic interactions contribute to skeletal muscle fatigue?

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Na+-K+ pumps in the transverse tubular system of skeletal muscle fibers preferentially use ATP from glycolysis.

The Na(+)-K(+) pumps in the transverse tubular (T) system of a muscle fiber play a vital role keeping K(+) concentration in the T-system sufficiently low during activity to prevent chronic depolarization and consequent loss of excitability. These Na(+)-K(+) pumps are located in the triad junction, the key transduction zone controlling excitation-contraction (EC) coupling, a region rich in glyco...

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Transverse tubular system depolarization reduces tetanic force in rat skeletal muscle fibers by impairing action potential repriming.

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ACELL March 47/3

Dutka, T. L., and G. D. Lamb. Effect of lactate on depolarization-induced Ca21 release in mechanically skinned skeletal muscle fibers. Am. J. Physiol. Cell Physiol. 278: C517–C525, 2000.—It is unclear whether accumulation of lactate in skeletal muscle fibers during intense activity contributes to muscle fatigue. Using mechanically skinned fibers from rat and toad muscle, we were able to examine...

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Effects of ionic parameters on behavior of a skeletal muscle fiber model

All living cells have a membrane which separates inside the cell from it's outside. There is a potential difference between inside and outside of the cell. This potential difference will change during an action potential. It is quite common to peruse action potentials of skeletal muscle fibers with the Hodgkin-Huxley model. Since Hodgkin and Huxley summarized some controlling currents like inwa...

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تاریخ انتشار 2007